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—ends— Notes to editors AstraZeneca submit a regulatory submission to the European Union (EU) contained by January 2004, all for two indication associated to the NSAID-associated upper GI symptom subtlety of items for NexiumÒ. These indications are for the utilize of NexiumÒ for the curing of NSAID-associated GU and the blocking of NSAID-associated GU/DU in patients at arbitrariness, necessitate continuous NSAID psychiatric therapy.

AstraZeneca be a leading transnational Healthcare commercial affianced in the research, fortification, crop and marketing of prescription pharmaceuticals and the secure of Healthcare services. It is one of the world’s governing pharmaceutical company along Healthcare sale of over and done with $18.8 billion and leading situation in sales of gastrointestinal, oncology, cardiovascular, neuroscience and respiratory products. AstraZeneca is down in the Dow Jones Sustainability Index (Global and European) by the use of powerfully as the FTSE4Good Index. NexiumÒ is a retail dirt of the AstraZeneca delivery of companies.

2. Goldstein JL et al. The comparative healing of gastric ulcer with esomeprazole versus ranitidine in patients taking any unbounded COX-2 selective NSAIDs or non-selective NSAIDs.

Abstract presented at EULAR, Berlin, Germany 2004.

3. Buttgereit F at al. Gastrointestinal venomous side-effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific inhibitors. Am J Med 2001; 110 (Suppl 3A): 13S-19S.

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5. Langman MJ et al. Adverse upper gastrointestinal effects of rofecoxib associate with NSAIDs. JAMA 1999; 282: 1929-1933.

6. Laine L. Non-steroidal anti-inflammatory linctus gastroplasty. Gastrointest Endosc Clin N Am 1996; 6: 489-504.

University of Florida researchers include begin a clinical exploration of oral insulin to obstruct or deferment implicated 1 diabetes bordered by populace at stake in support of the microbe.

8. People with Arthritis and Rheumatism in Europe (PARE) Manifesto Steering Group. European understanding belief sample 2004. Data opposed to wallet, PARE.

9. Miner P Jr et al. Gastric bristly stability with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover workroom. Am J Gastroenterol 2003; 98(12): 2616-2620.

10. Scheiman JM et al. Esomeprazole resolve heartburn and acid regurgitation in patients taking continuous NSAIDs, with COX-2 selective NSAIDs. Abstract presented at EULAR, Berlin, Germany 2004.

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